Melphalan Study guides, Class notes & Summaries

BMTCN ATG - correct answer anti t-cell globulin prevents GVHD, graft failure premeds: Tylenol, corticosteroids, Benadryl SE: hypotension, chills, rigors, fevers, pulmonary edema serum sickness - correct answer ATG myalgias, arthralgias, fever, rash, hand/facial edema give steroids BCNU (carmustine) - correct answer alkylating agent pre/post hydration SE: n/v, nephrotoxicity (elevated creat), pulmonary toxicity (pulmonary fibrosis, acute lung injury) infusion rx: feeling drunk, hy...

BMTCN Chapter 4 Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and Question and answers correctly solved 2023/2024What is the most important rationale for giving total body irradiation in multiple fractions? A. It is easier for patients. B. It decreases short-term side effects. C. It decreases long-term side effects. D. It is easier for radiation staff. - correct answer C. It decreases long-term side effects. What change can decrease side effects of busulfan? A....

BMTCNTypical dose of G-CSF given during mobilization process - correct answer 10 mcg/kg per day Upper dosage limit of G-CSF given during mobilization process - correct answer 32 mcg/kg per day How many doses/days of filgrastim typically given before starting collection? - correct answer 4-5 days What volume of blood is typically processed when collecting from a pediatric donor? - correct answer 200-250 mL/kg What is the typical cut-off age for peripheral stem cell donation? - correct...

BMTCN Exam Questions & Answers 2023/2024 What type of transplants commonly have PTLD as a secondary malignancy? - ANSWER-Allo HSCT with T-cell depleted graft Therapies associated with therapy-related acute leukemia and MDS - ANSWER-alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. doxorubicin, etoposide, mitoxantrone) Genetic predispositions that increase risk of primary and secondary cancers - ANSWER-neurofibromatosis ...

BMTCN Chapter 4: Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and EngraftmentWhat is the most important rationale for giving total body irradiation in multiple fractions? A. It is easier for patients. B. It decreases short-term side effects. C. It decreases long-term side effects. D. It is easier for radiation staff. - correct answer C. It decreases long-term side effects. What change can decrease side effects of busulfan? A. Using oral busulfan B. Basing the...

BMTCN ch.04 Question and answers rated A+ 2023/2024preparative regimens - correct answer aka conditioning regiment part of HSCT when tx malignant diseases goal: eradicate residual disease and/or provide immunosuppression to prevent graft rejection prepare receipients bone marrow to accept new donor cells examples of chemo - correct answer cyclophosphamide busulfan etoposide cytarabine carmustine melphalan myeloablative regimens - correct answer lethal doses of chemo (usually includ...

BMTCN What type of transplants commonly have PTLD as a secondary malignancy? - ANSWER-Allo HSCT with T-cell depleted graft Therapies associated with therapy-related acute leukemia and MDS - ANSWER-alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. doxorubicin, etoposide, mitoxantrone) Genetic predispositions that increase risk of primary and secondary cancers - ANSWER-neurofibromatosis type 1, Fanconi anemia Risk factors fo...

BMTCNATG - correct answer anti t-cell globulin prevents GVHD, graft failure premeds: Tylenol, corticosteroids, Benadryl SE: hypotension, chills, rigors, fevers, pulmonary edema serum sickness - correct answer ATG myalgias, arthralgias, fever, rash, hand/facial edema give steroids BCNU (carmustine) - correct answer alkylating agent pre/post hydration SE: n/v, nephrotoxicity (elevated creat), pulmonary toxicity (pulmonary fibrosis, acute lung injury) infusion rx: feeling drunk, hypo...

BMTCNTypical dose of G-CSF given during mobilization process - correct answer 10 mcg/kg per day Upper dosage limit of G-CSF given during mobilization process - correct answer 32 mcg/kg per day How many doses/days of filgrastim typically given before starting collection? - correct answer 4-5 days What volume of blood is typically processed when collecting from a pediatric donor? - correct answer 200-250 mL/kg What is the typical cut-off age for peripheral stem cell donation? - correct...

ONS FUNDAMENTALS (ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY) TUDY GUIDE EXAM 2024 when chemo is used before primary treatment (surgery) to reduce the size of a tumor - CORRECT ANSWER-neoadjuvant therapy neoadjuvant therapy is common for what 2 kind of cancers? - CORRECT ANSWERcolon and breast when chemo is used after primary (surgery, radiation) - CORRECT ANSWER-adjuvant induction - CORRECT ANSWER-start of chemo consolidation - CORRECT ANSWER-testing labs and such after chemo myeloblation ...