Alkylating agents Study guides, Class notes & Summaries

Chemotherapy/Immunotherapy Certificate Course (ONS,ONCC) QUESTIONS AND CORRECT ANSWERS 2024 Alkylating agents - CORRECT ANSWER-Classification Break DNA helix strand, thereby interfering with DNA replication Altretamine (Hexalen) - CORRECT ANSWER-Alkylating Agent PO Ovarian CA Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression Bendamustine (Treanda/Bendeka) - CORRECT ANSWER-Alkylating...

CPHON Exam 93 Questions with Verified Answers G1 - CORRECT ANSWER The first gap, or growth phase, of the cell cycle, consisting of the portion of interphase before DNA synthesis begins. Cell grows larger and produces ribosome and proteins. S - CORRECT ANSWER All 46 chromosomes are replicated in the cells nucleus G2 - CORRECT ANSWER The second gap, or growth phase, of the cell cycle, consisting of the portion of interphase after DNA synthesis occurs. DNA is condensed into rod form . (...

Alkylating agents - ANSWER Classification Break DNA helix strand, thereby interfering with DNA replication Altretamine (Hexalen) - ANSWER Alkylating Agent PO Ovarian CA Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression Bendamustine (Treanda/Bendeka) - ANSWER Alkylating agent IV CLL or Indolent NHL Side effects- pyrexia, nausea, vomiting, skin reactions, TLS, hepatotoxicity, vein irr...

3 major phases of cell division: Interphase Mitotic phase Cytokinesis 3 steps of interphase: First growth phase (G1) Synthesis phase (S phase) Second growth phase (G2) 4 phases of mitosis: Prophase Metaphase Anaphase Telophase Innate immunity: Non-specific response, either: 1. Barrier (skin, mucous membranes, flora of skin/gut) 2. Cellular components (phagocytes, natural killer cells, granulocytes, macrophages) Adaptive immunity: Follows innate immunity ...

CPHON Exam 195 Questions with Verified Answers Classification of Methotrexate - CORRECT ANSWER antimetabolite (s-phase) Classification of mercaptopurine and thioguinine - CORRECT ANSWER antimetabolite(s-phase) Classification of fludarabine/nelarabine - CORRECT ANSWER anti-metabolite Classification of cytarabine/gemcitabine - CORRECT ANSWER antimetabolite Classification and sub-class of ironotecan/topotecan - CORRECT ANSWER Topoisomerase inhibitors (campotothecins) Classificatio...

ONS fundamentals exam questions & answers 2023/2024 when chemo is used before primary treatment (surgery) to reduce the size of a tumor - ANSWER-neoadjuvant therapy neoadjuvant therapy is common for what 2 kind of cancers? - ANSWER-colon and breast when chemo is used after primary (surgery, radiation) - ANSWER-adjuvant induction - ANSWER-start of chemo consolidation - ANSWER-testing labs and such after chemo myeloblation - ANSWER-destroying the bone marrow in order to a trans...

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy Main benefit of neoadjuvant chemotherapy (breast cancer patient) A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of morbidity and ...

HESI Pharmacology Exam Questions & Answers Version 1 2023 Update A nurse is caring for a client with hyperparathyroidism and notes that the client's serum calcium level is 13 mg/dL. Which medication should the nurse prepare to administer as prescribed to the client? Calcitonin (Miacalcin) Rationale: The normal serum calcium level is 8.6 to 10.0 mg/dL. This client is experiencing hypercalcemia. Calcium gluconate and calcium chloride are medications used for the treatment of tetany, w...

CSO Exam 2024 Study Guide with Compete Solutions Alkylating agents - Correct Answer synthetic chemicals containing alkyl groups that attack DNA, causing strand breaks thus preventing replication and transcription of RNA Examples: Bendamustine (Treanda), Busulfan (Myleran PO/Busulflex IV, Carboplatin (paraplatin), Carmustine (BCNU), Chlorambucil (Leukeran), Ciosplatin (Platinol, CDDP), Cyclophosphamide (Cytoxan, CTX), Dacarbazine (DTIC), Ifosfamide (Ifex), Mechlorethamine (nitrogen mustard),...

Pharmacology for Nurses 6th Edition A Pathophysiological Approach by Michael P. Adams; Norman Holland; Carol Quam Urban 8334, 0 , 8438, 5 1 Introduction to Pharmacology 1.1 History of Pharmacology 1.2 Pharmacology: The Study of Medicines 1.3 Pharmacology and Therapeutics 1.4 Classification of Therapeutic Agents as Drugs, Biologics, Biosimilars, and Complementary and Alternative Medicine Therapies 1.5 Therapeutic and Pharmacologic Classification of Drugs 1.6 Chemical, Generi...