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NURP 532-Rheum Exam Questions And Correct Answers

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  • September 22, 2024
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  • gout ss
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NURP 532-Rheum Exam
Questions And Correct Answers

stages of gout progression - Answer stage 1-high uric acid levels: uric acid builds up in
blood, crystallization in joints

stage 2-acute gout: symptoms start, pain in affected areas

stage 3-intercritical gout:remission between attacks

stage 4-chronic gout: pain is frequent and tophi form in joints

Gout S/S - Answer Rapid onset (pain peaks in 1 day)

Hot, red, swollen joint (usually 1 joint only)

Pain worse at night/rest "bedsheet pain"

PE=Most common locations:

-First metatarsophalangeal joint

-Followed by midtarsal joints, ankles, knees, fingers

Red, hot, exquisitely tender joint

Absence of fever

Tophi in chronic disease

Gout risk factors - Answer -Use of loop or thiazide diuretics

-Men or postmenopausal women (female sex hormones increase excretion of uric acid)

-Increased age

-Black

-Obesity

-Diet: EtOH intake, organ meat, shellfish, sugary food/drinks

dif dx for gout - Answer Septic joint arthritis (fever, elevated WBC; need to get
arthrocentesis if thinking this)

Cellulitis (possible fever/elevated WBC, usually located more over soft tissue)

,Bursitis (profound swelling d/t enlarged bursa)

Lyme (+titres, systemic sx)

Pseudogout (normal serum uric acid levels but +crystals)

Trauma (elicited on history)

Osteoarthritis (chronic onset)

Rheumatoid arthritis (polyarticular, often symmetrical)

diagnosing gout - Answer JOINT FLUID ASPIRATION- Gold standard for Diagnosis

-(AKA Arthrocentesis) Presence of intracellular monosodium urate crystals in synovial
fluid

SERUM URIC ACID- elevated

-Commonly checked but NOT diagnostic of gout

-May be normal or even low during an active flare;

most gout patients will have elevations in between flares

-Therefore, best measured in between flares to monitor response to uric acid
lowering/preventative treatments

Imaging (U/S, MRI, CT) not usually needed unless there is trauma/diagnostic uncertainty

American College of Rheumatology Diagnostic Criteria- Gout - Answer Presence of
characteristic urate crystals in the joint fluid

or

Presence of a tophus proven to contain urate crystals by chemical means or polarized
light microscopy

or

Presence of six or more of the following clinical, laboratory, or radiologic findings:

-Asymmetric swelling within a joint on radiography

-Attack of monoarticular arthritis

-Culture of joint fluid negative for microorganisms during attack of joint inflammation

-Development of maximal inflammation within one day

-Hyperuricemia

-Joint redness

, -More than one attack of acute arthritis

-Pain or redness in the first metatarsophalangeal joint

-Subcortical cyst without erosions on radiography

-Suspected tophus

-Unilateral attack involving first metatarsophalangeal joint

-Unilateral attack involving tarsal joint

Gout tx - Answer acute=NSAIDS, Colchicine, Corticosteroids

prophylactic=Allopurinol, Colchicine, Probenecid

-Initiate if: tophi, hx of kidney stones, 2+ gout flares per year, (1+ flares per year if CKD
stage 2 or higher)

-Goal is to bring uric acid level <6 mg per dL

-Continue 3-6 mons after active flare, indefinitely if there are tophi and/or ongoing sx

-DO NOT start Allopurinol during active gout flare!

non-pharm mgmt of Gout - Answer -encourage weight loss if overweight/obese

-limit sugary foods/ HFCS intake

-avoid ETOH

-limit high purine organ meats (beef, lamb, pork, shellfish)

-inc low fat dairy and vegetables

Juvenile Idiopathic Arthritis (JIA) - Answer assess for=

-Joint redness

-Family history

-Limping/limited movement (can be secondary to pain AND/OR joint contractures)

-Rash (non-pruritic, erythematous, trunk and proximal extremities)

diagnostic criteria for JIA - Answer 1) Onset before age 16 years

2) Arthritis involving one or more joints or at least two of the following findings:

Limitation in range of motion (ROM)

Tenderness or pain with joint movement

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