Lehne's Pharmacology for Nursing Care, 12th Edition
Test Bank Complete_
Lehne's Pharmacology for Nursing Care, 12th Edition,
Jacqueline Rosenjack Burchum DNSc FNP-BC CNE (Author), Laura D. Rosenthal
DNP RN ACNP-BC FAANP (Author)
All chapters 1-113; 2024
12th Edition
, Lehne's Pharmacology for Nursing Care, 12th Edition
Table of Contents
UNIT I: INTRODUCTION ...................................................................................................................................... 6
Chapter 1: Orientation To Pharmacology ................................................................................................................ 6
Chapter 2: Application Of Pharmacology In Nursing Practice ............................................................................... 8
Chapter 3: Drug Regulation, Development, Names, And Information ................................................................. 19
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY.................................................................................. 25
Chapter 4: Pharmacokinetics ................................................................................................................................ 25
Chapter 5: Pharmacodynamics .............................................................................................................................. 38
Chapter 6: Drug Interactions ................................................................................................................................. 45
Chapter 7: Adverse Drug Reactions And Medication Errors ................................................................................ 58
Chapter 8: Individual Variation In Drug Responses.............................................................................................. 71
Chapter 9: Genetic And Genomic Considerations ................................................................................................. 81
Chapter 10: Introduction To Immunomodulators ................................................................................................ 105
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN .............................................................................. 127
Chapter 11: Drug Therapy In Geriatric Patients .................................................................................................. 127
Chapter 12: Drug Therapy In Pediatric Patients ................................................................................................. 140
Chapter 13: Drug Therapy In Older Adults ........................................................................................................ 150
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS ................................................................................ 156
SECTION 1: INTRODUCTION ..................................................................................................................... 156
Chapter 14: Basic Principles Of Neuropharmacology..................................................................................... 156
Chapter 15: Physiology Of The Peripheral Nervous System........................................................................... 165
SECTION 2: CHOLINERGIC DRUGS ......................................................................................................... 174
Chapter 16: Muscarinic Agonists .................................................................................................................... 174
Chapter 17: Muscarinic Antagonists ............................................................................................................... 184
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis ................................................. 189
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ............................................................... 197
SECTION 3: ADRENERGIC DRUGS ........................................................................................................... 206
Chapter 20: Adrenergic Agonists .................................................................................................................... 206
Chapter 21: Adrenergic Antagonists................................................................................................................ 219
Chapter 22: Indirect-Acting Antiadrenergic Agents........................................................................................ 235
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ........................................................................................ 246
SECTION 1: INTRODUCTION ..................................................................................................................... 246
Chapter 23: Introduction To Central Nervous System Pharmacology ............................................................ 246
SECTION 2: DRUGS FOR NEURODEGENERATIVE DISORDERS ...................................................... 253
Chapter 24: Drugs For Parkinson’s Disease .................................................................................................... 253
Chapter 25: Alzheimer’s Disease .................................................................................................................... 268
Chapter 26: Drugs For Multiple Sclerosis ....................................................................................................... 277
SECTION 3: NEUROLOGIC DRUGS........................................................................................................... 289
Chapter 27: Drugs For Seizure Disorders ........................................................................................................ 289
Chapter 28: Drugs For Muscle Spasm And Spasticity .................................................................................... 308
, Lehne's Pharmacology for Nursing Care, 12th Edition
SECTION 4: DRUGS FOR PAIN ................................................................................................................... 316
Chapter 29: Local Anesthetics ......................................................................................................................... 316
Chapter 30: General Anesthetics ..................................................................................................................... 326
Chapter 31: Opioid Analgesics, Opioid Antagonists, And NonopioidCentrally Acting Analgesics ............... 339
Chapter 32: Pain Management In Patients With Cancer ................................................................................. 353
Chapter 33: Drugs For Headache .................................................................................................................... 370
SECTION 5: PSYCHOTHERAPEUTIC DRUGS ........................................................................................ 380
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia .............................................................. 380
Chapter 35: Antidepressants ............................................................................................................................ 395
Chapter 36: Drugs For Bipolar Disorder ......................................................................................................... 412
Chapter 37: Sedative-Hypnotic Drugs ............................................................................................................. 424
Chapter 38: Management Of Anxiety Disorders ............................................................................................. 441
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/HyperactivityDisorder ................... 449
SECTION 6: SUBSTANCE USE DISORDERS ............................................................................................ 460
Chapter 40: Substance Use Disorders I: Basic Considerations ....................................................................... 460
Chapter 41: Substance Use Disorders II: Alcohol ........................................................................................... 468
Chapter 42: Substance Use Disorders III: Nicotine ........................................................................................ 486
Chapter 43: Substance Use Disorders IV: Major Drugs Of Abuse Other Than Alcohol And Nicotine .......... 496
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE ......................................... 515
Chapter 44: Diuretics ........................................................................................................................................... 515
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ................................................... 526
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD............................. 539
Chapter 46: Review Of Hemodynamics .............................................................................................................. 539
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System ...................................................... 546
Chapter 48: Calcium Channel Blockers .............................................................................................................. 558
Chapter 49: Vasodilators ..................................................................................................................................... 565
Chapter 50: Drugs For Hypertension................................................................................................................... 575
Chapter 51: Drugs For Heart Failure ................................................................................................................... 594
Chapter 52: Antidysrhythmic Drugs .................................................................................................................... 612
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels ................................................. 632
Chapter 54: Drugs For Angina Pectoris............................................................................................................... 658
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ................................................................... 673
Chapter 56: Management Of ST-Elevation Myocardial Infarction ..................................................................... 690
Chapter 57: Drugs For Hemophilia ..................................................................................................................... 699
Chapter 58: Drugs For Deficiency Anemias ....................................................................................................... 710
Chapter 59: Hematopoietic Agents ...................................................................................................................... 723
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ................................................................................... 733
Chapter 60: Drugs For Diabetes Mellitus ............................................................................................................ 733
Chapter 61: Drugs For Thyroid Disorders ........................................................................................................... 748
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function ................................................................ 761
Chapter 63: Drugs For Disorders Of The Adrenal Cortex................................................................................... 771
, Lehne's Pharmacology for Nursing Care, 12th Edition
UNIT IX: REPRODUCTIVE HEALTH ............................................................................................................ 782
Chapter 64: Estrogens And Progestins: Basic Pharmacology And NoncontraceptiveApplications .................... 782
Chapter 65: Birth Control .................................................................................................................................... 792
Chapter 66: Drug Therapy Of Infertility ............................................................................................................. 806
Chapter 67: Drugs That Affect Uterine Function ................................................................................................ 818
Chapter 68: Androgens ........................................................................................................................................ 830
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ............................................... 842
Chapter 70: Transgender Health ......................................................................................................................... 852
UNIT X: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ........................ 859
Chapter 71: Review Of The Immune System ..................................................................................................... 859
Chapter 72: Childhood Immunization ................................................................................................................. 870
Chapter 73: Immunosuppressants ........................................................................................................................ 886
Chapter 74: Antihistamines ................................................................................................................................. 899
Chapter 75: Cyclooxygenase Inhibitors: Nonsteroidal Anti-Inflammatory Drugs AndAcetaminophen............. 914
Chapter 76: Glucocorticoids In Nonendocrine Disorders ................................................................................... 929
UNIT XI: DRUGS FOR BONE AND JOINT DISORDERS ............................................................................ 942
Chapter 77: Drug Therapy Of Rheumatoid Arthritis ........................................................................................... 942
Chapter 78: Drug Therapy Of Gout..................................................................................................................... 951
Chapter 79: Drugs Affecting Calcium Levels And Bone Mineralization............................................................ 959
UNIT XII: RESPIRATORY TRACT DRUGS .................................................................................................. 975
Chapter 80: Drugs For Asthma And Chronic Obstructive Pulmonary Disease .................................................. 975
Chapter 81: Drugs For Allergic Rhinitis, Cough, And Colds ............................................................................ 1003
UNIT XIII: GASTROINTESTINAL DRUGS ................................................................................................. 1016
Chapter 82: Drugs For Peptic Ulcer Disease ..................................................................................................... 1016
Chapter 83: Laxatives ....................................................................................................................................... 1027
Chapter 84: Other Gastrointestinal Drugs ......................................................................................................... 1039
UNIT XIV: NUTRITION AND COMPLIMENTARY THERAPY ............................................................... 1060
Chapter 85: Vitamins ......................................................................................................................................... 1060
Chapter 86: Drugs For Weight Loss .................................................................................................................. 1076
Chapter 87: Complementary And Alternative Therapy ..................................................................................... 1092
UNIT XV: THERAPY OF INFECTIOUS DISEASES ................................................................................... 1099
Chapter 88: Basic Principles Of Antimicrobial Therapy................................................................................... 1099
Chapter 89: Drugs That Weaken The Bacterial Cell Wall I: Penicillins ........................................................... 1113
Chapter 90: Drugs That Weaken The Bacterial Cell Wall II: Other Drugs ...................................................... 1129
Chapter 91: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides,And Others ................ 1140
Chapter 92: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis.................................................... 1159
Chapter 93: Sulfonamides And Trimethoprim .................................................................................................. 1176
Chapter 94: Drug Therapy Of Urinary Tract Infections .................................................................................... 1188
Chapter 95: Antimycobacterial Agents: Drugs For Tuberculosis ..................................................................... 1203
Chapter 96: Miscellaneous Antibacterial Drugs: Fluoroquinolones, Metronidazole,Daptomycin, Rifampin,
Rifaximin, And Fidaxomicin ............................................................................................................................ 1224
, Lehne's Pharmacology for Nursing Care, 12th Edition
Chapter 97: Antifungal Agents .......................................................................................................................... 1232
Chapter 98: Antiviral Agents I: Drugs For Non-HIV Viral Infections ............................................................. 1252
Chapter 99: Antiviral Agents II: Drugs For HIV Infection And Related OpportunisticInfections ................... 1264
Chapter 100: Drug Therapy Of Sexually Transmitted Diseases ....................................................................... 1278
Chapter 101: Antiseptics And Disinfectants...................................................................................................... 1290
UNIT XVI: CHEMOTHERAPY OF PARASITIC DISEASES ..................................................................... 1300
Chapter 102: Anthelmintics ............................................................................................................................... 1300
Chapter 103: Antiprotozoal Drugs I: Antimalarial Agents................................................................................ 1309
Chapter 104: Antiprotozoal Drugs II: Miscellaneous Agents ........................................................................... 1320
Chapter 105: Ectoparasiticides .......................................................................................................................... 1329
UNIT XVII: CANCER CHEMOTHERAPY ................................................................................................... 1340
Chapter 106: Basic Principles Of Cancer Treatment ........................................................................................ 1340
Chapter 107: Anticancer Drugs I: Cytotoxic Agents ......................................................................................... 1364
Chapter 108: Anticancer Drugs II: Hormonal Agents, Targeted Drugs, And OtherNoncytotoxic Anticancer
Drugs ................................................................................................................................................................. 1381
UNIT XVIII: MISCELLANEOUS DRUGS AND THERAPIES ................................................................... 1393
Chapter 109: Drugs For The Eye ....................................................................................................................... 1393
Chapter 110: Drugs For The Skin...................................................................................................................... 1407
Chapter 111: Drugs For The Ear ....................................................................................................................... 1425
UNIT XIX: TOXICOLOGY .............................................................................................................................. 1457
Chapter 112: Management Of Poisoning .......................................................................................................... 1457
Chapter 113: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ...................................... 1465
, Lehne's Pharmacology for Nursing Care, 12th Edition
UNIT I: INTRODUCTION
Chapter 1: Orientation To Pharmacology
Test Bank, Jacqueline R. Burchum: Lehne’s Pharmacology For Nursing Care, 12th Edition
MULTIPLE CHOICE
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do This,
TheNurse Will Rely On Knowledge Of:
a. Clinical Pharmacology.
b. Drug Efficacy.
c. Pharmacokinetics.
d. Pharmacotherapeutics.
CORRECT ANS: D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent
Conditions. Clinical Pharmacology Is Concerned With All Aspects Of Drug–Human Interactions.
Drug Efficacy Measures The Extent To Which A Given Drug Causes An Intended Effect.
Pharmacokinetics Is The Study Of The Impact Of The Body On A Drug.
DIFFICULY: Cognitive Level:
Comprehension REF: Four Basic Terms
TOPIC: Nursing Process: Implementation
MAIN SUBJECT CATEGORY: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic
And Parenteral Therapies
2. What Does It Mean When A Drug Is Described As Easy To Administer?
a. It Can Be Stored Indefinitely Without Need For Refrigeration.
b. It Does Not Interact Significantly With Other Medications.
c. It Enhances Patient Adherence To The Drug Regimen.
d. It Is Usually Relatively Inexpensive To Produce.
CORRECT ANS: C
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are
MoreLikely To Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The
Other Attributes Listed, But Those Properties Are Independent Of Ease Of Administration.
DIFFICULY: Cognitive Level: Comprehension
REF: Additional Properties Of An Ideal Drug: Ease Of
AdministrationTOPIC: Nursing Process: Assessment
MAIN SUBJECT CATEGORY: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic
And Parenteral Therapies
3. A Patient Tells The Nurse That He Was Told By The Prescriber That The Analgesic He Is Taking
Is Very Effective. Which Statement By The Patient Demonstrates An Understanding Of The
Drug’sEffectiveness?
a. “I Don’t Have To Worry About Toxicity, Since It Takes A Large Amount Of This Drug
ToCause An Overdose.”
b. “It Has No Side Effects And Doesn’t Interact With Other Drugs.”
c. “I Only Have To Take It Every 12 Hours.”
d. “It Might Make Me Sleepy, And It Lessens Pain For Several Hours At A Time.”
CORRECT ANS: D
