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Oral And Maxillofacial Pathology Exam 1 With Complete Solutions Latest Update

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Oral And Maxillofacial Pathology Exam 1 With Complete Solutions Latest Update

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  • July 18, 2024
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  • 2023/2024
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Oral And Maxillofacial Pathology Exam 1 With
Complete Solutions Latest Update

Formation of the Lips - correct answers Middle portion of the upper lip: Formed by
the fusion of the

medial nasal process of both sides along with the frontonasal

process



Lateral portion of the upper lip: Fusion of the maxillary

processes of each side and medial nasal process



Lower lip: Formed by the fusion of the two mandibular processes



Cleft percentage - correct answers Any defect in the development of these
processes

or their fusion may result in orofacial clefts



Cleft lip- 25%

Cleft palate - 30%

Cleft lip and palate - 45%



CL ± CP are related etiologically and

,Isolated CP is a separate entity



ETIOLOGY of CL ± CP - correct answers Syndrome-associated: 250 developmental
syndromes (3% to 8%

of total clefts)



Single gene mutations; AD, AR or X-linked

Chromosomal abnormalities

Idiopathic

multifactorial



Incidence of Orofacial Clefts - correct answers Most common congenital
abnormality in humans



Racial variation of CL ± CP: White - 1 in 700 to 1000

Asian - 1.5 in 700 to 1000

Black - 0.4 per 1000

Native Americans - 3.6 per 1000



Isolated CP is much less common



Isolated CL: Males > Females (1.5:1)

CL + CP: Males > Females (2:1)

,Isolated CP: Females > Males



80% of isolated CL: Unilateral (70% occur on left side)



Complete CL vs Incomplete CL




NATIVE AMERICANS HIGHEST

BLACKS LOWEST



Variation in CP - correct answers Hard and soft palate or soft palate alone



Most minimal involvement: Bifid Uvula



Bifid Uvula: Most common

(1 in 80 in Whites;

1 in 10 in Asians and Native

Americans;

1 in 250 in Blacks)



Submucous palatal cleft: Defect in

underlying musculature alone;

, A notch in bone also noted



Pierre Robin Sequence (Pierre Robin Anomalad) - correct answers Mandibular
micrognathia: Prevents descending of the tongue causing CP

Cleft palate: Wider and U-shaped than regular CP

3. Glossoptosis: Causing airway obstruction



Stigma of Orofacial clefts - correct answers Clinical appearance: psychological
problems

Feeding and speech difficulties

Malocclusion due to collapse of the maxillary arch



Treatment: Multidisciplinary approach



Genetic counseling: Risk for cleft development in a sibling or

offspring is 3% to 5%



Risk increases to 10% to 20% if there is are affected first degree

relatives



Lateral Facial Cleft: - correct answers Caused by lack of fusion of the maxillary and

mandibular process

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