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Pharmacology NCLEX 2022 questions and answers(100% Verified)
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Pharmacology NCLEX 2022 questionsand answers(100% Verified)
The nurse is administering the drug losartan (Cozaar) to a client with impaired liver
function. Recognizing this medication is a prodrug, the nurse monitors what effect?
correct answer- Reduction in the desired effect
What pharmacokinetic property makes it difficult to treat a patients brain tumor? correct
answer- blood-brain barrier
The nurse administering an acidic drug to a client, and determines that drug absorption
will be enhanced if the drug is administered:
a) with milk
b) on an empty stomach
c) with other acidic medications
d) after a lipid-soluble meal correct answer- b
A client with cirrhosis of the liver exhibits decreased metabolic activity. The nurse
anticipates which possible change in the client's drug regimen?
a) a reduction in the dosage of drugs
b) an increase in the dosage of drugs correct answer- a
A client with renal failure is at particular risk for what condition? correct answer- rapid
development of drug toxicity
The nurse is preparing to dicharge a patient who has received one last dose of a
medication that has a half-life of 7 days. What should the nurse tell the client? correct
answer- That they might continue to experience effects of the drug for several days
A client is started on a thyroid hormone and has blood drawn to measure the plasma
concentration of the drug. The nurse explains that this will identify if: correct answer- the
drug is in the therapeutic range
In situations in which it is critical to raise a client's drug plasma level quickly, what
should the nurse be prepared to administer? correct answer- loading dose
When administering oral medications to a client, the nurse recognizes that some drugs
might be completely metabolized by the liver circulation before entering general
circulation. This effect is known as ___________. correct answer- first-pass effect
, If the nurse administers medications to a client with renal failure, it is imperative that the
client be assessed for what development? correct answer- drug toxicity
In what phase of the dose-response curve should the nurse expect a medication to be
in the most desirable range of doses?
a) Phase 2
b) Phase 3
c) Phase 4
d) Phase 1 correct answer- a
The nurse is administering a drug that will produce a therapeutic effect at a lower dose
compared with another drug in the same class. the nurse recognizes that the first drug
is considered:
a) More efficacious
b) Less toxic
c) More potent
d) More toxic correct answer- c
The nurse informs a client receiving antibiotic therapy that the drug being administered
is the one more efficacious for the client's infection. When the client asks what this
means, the nurse explains:
a) It is more potent that your other medication.
b) it is less toxic than other anitbiotics
c) It has fewer side effects than most other drugs.
d) It will have the desired response against the infection correct answer- d
When considering the pharmacotherapeutic effects of drugs administered to clients, the
nurse considers which property of most importance:
a) Efficacy
b) Interaction with other drugs
c) Potency
d) Toxicity correct answer- a
When administering a drug that has agonist properties, the nurse recognizes it will have
what effect?
a) It will occupy the receptor, and block it from action.
b) It will partially block the action of the receptor.
c) It will minimize the effect of the receptor module.
d) It will mimic the action of the receptor to which it binds correct answer- d
A client receiving a histamine antagonist asks the nurse how the drug works in the
body. The nurse explains:
a) It mimics the action of the chemical histamine
b) It is a precursor to the histamine molecule naturally produced by your body.
c) It blocks the action of histamine in your stomach.
d) It stimulates the action of histamine in your stomach correct answer- c
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